List of Publication

2017

  • Tomiyama R, Takakura K, Takatou S, Le TM, Nishiuchi T, Nakamura Y, Konishi T, Matsugo S, Hori O. 3,4-dihydroxybenzalacetone and caffeic acid phenethyl ester induce preconditioning ER stress and autophagy in SH-SY5Y cells. J Cell Physiol. 2017 Jul 6. doi: 10.1002/jcp.26080. [Epub ahead of print]
  • Takano K, Ishida N, Kawabe K, Moriyama M, Hibino S, Choshi T, Hori O, Nakamura Y. A dibenzoylmethane derivative inhibits lipopolysaccharide-induced NO production in mouse microglial cell line BV-2. Neurochem Int. 2017 Apr 5. pii: S0197-0186(17)30133-X. doi: 10.1016/j.neuint.2017.04.002. [Epub ahead of print]
  • Hattori T, Kaji M, Ishii H, Jureepon R, Takarada-Iemata M, Minh Ta H, Manh Le T, Konno A, Hirai H, Shiraishi Y, Ozaki N, Yamamoto Y, Okamoto H, Yokoyama S, Higashida H, Kitao Y, Hori O. CD38 positively regulates postnatal development of astrocytes cell-autonomously and oligodendrocytes non-cell-autonomously. Glia. 2017, Mar 13.

2016

  • Higashida H, Kamimura SY, Inoue T, Hori O, Islam MS, Lopatina O, Tsuji C. Cyclic ADP-ribose as an endogenous inhibitor of the mTOR pathway downstream of dopamine receptors in the mouse striatum. J Neural Transm (Vienna). 2016 Dec 26. doi: 10.1007/s00702-016-1666-7.
  • Ta MH, Le MT, Ishii H, Takarada-Iemata M, Hattori T, Hashida K, Yamamoto Y, Mori K, Takahashi R, Kitao Y, Hori O. Atf6α deficiency suppresses microglial activation and ameliorates pathology of experimental autoimmune encephalomyelitis. Journal of Neurochemistry, 2016, in press.
  • Le MT, Hashida K, Ta MH, Takarada-Iemata M, Kokame K, Kitao Y, Hori O. Deletion of Herpud1 enhances heme oxygenase-1 expression in a mouse model of Parkinson’s disease. Parkinson’s Dis. 2016 in press

2015

  • Kezuka D, Takarada-Iemata M, Hattori T, Mori K, Takahashi R, Kitao Y, Hori O. Deletion of Atf6α enhances kainate-induced neuronal death in mice. Neurochem Int. 2016 Jan;92:67-74. doi: 10.1016/j.neuint.2015.12.009. Epub 2015 Dec 25.
  • Transgenic supplementation of SIRT1 fails to alleviate acute loss of nigrostriatal dopamine neurons and gliosis in a mouse model of MPTP-induced parkinsonism.Kitao Y, Ageta-Ishihara N, Takahashi R, Kinoshita M, Hori O.F1000Res. 2015 May 27;4:130. doi: 10.12688/f1000research.6386.1. eCollection 2015
  • Koyama Y, Hattori T, Nishida T, Hori O, Tohyama M.
    Alterations in dendrite and spine morphology of cortical pyramidal neurons in DISC1-binding zinc finger protein (DBZ) knockout mice.
    Front Neuroanat. 2015 Apr 30;9:52. doi: 10.3389/fnana.2015.00052. eCollection 2015.
  • Miyata S, Hattori T, Shimizu S, Ito A, Tohyama M. Disturbance of Oligodendrocyte Function Plays a Key Role in the Pathogenesis of Schizophrenia and Major Depressive Disorder.
    Miyata S, Hattori T, Shimizu S, Ito A, Tohyama M.
    Biomed Res Int. 2015;2015:492367. Epub 2015 Feb 1. Review.
  • Okamoto M, Iguchi T, Hattori T, Matsuzaki S, Koyama Y, Taniguchi M, Komada M, Xie MJ, Yagi H, Shimizu S, Konishi Y, Omi M, Yoshimi T, Tachibana T, Fujieda S, Katayama T, Ito A, Hirotsune S, Tohyama M, Sato M.DBZ Regulates Cortical Cell Positioning and Neurite Development by Sustaining the Anterograde Transport of Lis1 and DISC1 through Control of Ndel1 Dual-Phosphorylation.J Neurosci. 2015 Feb 18;35(7):2942-58.
  • Tohyama M, Miyata S, Hattori T, Shimizu S, Matsuzaki S.Molecular basis of major psychiatric diseases such as schizophrenia and depression.
    AnatSci Int. 2015 Jan 17.
  • Yoshikawa A, Kamide T, Hashida K, Ta HM, Inahata Y, Takarada-Iemata M, Hattori T, Mori K, Takahashi R, Matsuyama T, Hayashi Y, Kitao Y, Hori O. Deletion of Atf6α impairs astroglial activation and enhances neuronal death following brain ischemia in mice. J Neurochem. 2015 Feb;132(3):342-53. doi: 10.1111/jnc.12981. Epub 2015 Jan 6

2014

  • Hieda Y, Anraku M, Choshi T, Tomida H, Fujioka H, Hatae N, Hori O, Hirose J, Hibino S. Antioxidant effects of the highly-substituted carbazole alkaloids and their related carbazoles. Bioorg Med Chem Lett. 2014 Aug 1;24(15):3530-3. doi: 10.1016/j.bmcl.2014.05.050. Epub 2014 May 27
  • Shimizu S, Koyama Y, Hattori T, Tachibana T, Yoshimi T, Emoto H, Matsumoto Y, Miyata S, Katayama T, Ito A, Tohyama M. DBZ, a CNS-specific DISC1 binding protein, positively regulates oligodendrocyte differentiation. Glia 2014 May;62(5):709-24.
  • Lopatina O, Yoshihara T, Nishimura T, Zhong J, Akther S, Fakhrul AA, Liang M, Higashida C, Sumi K, Furuhara K, Inahata Y, Huang JJ, Koizumi K, Yokoyama S, Tsuji T, Petugina Y, Sumarokov A, Salmina AB, Hashida K, Kitao Y, Hori O, Asano M, Kitamura Y, Kozaka T, Shiba K, Zhong F, Xie MJ, Sato M, Ishihara K, Higashida H. Anxiety- and depression-like behavior in mice lacking the CD157/BST1 gene, a risk factor for Parkinson's disease.Front Behav Neurosci. 2014 Apr 22;8:133. doi: 10.3389/fnbeh.2014.00133.
  • Takarada-Iemata M, Kezuka D, Takeichi T, Ikawa M, Hattori T, Kitao Y, Hori O. Deletion of N-myc downstream-regulated gene 2 attenuates reactive astrogliosis and inflammatory response in a mouse model of cortical stab injury. J Neurochem. 2014 Apr 3. doi: 10.1111/jnc.12729. [Epub ahead of print]
  • Hattori T, Shimizu S, Koyama Y, Emoto H, Matsumoto Y, Kumamoto N, Yamada K, Takamura H, Matsuzaki S, Katayama T, Tohyama M, Ito A. DISC1 (disrupted-in-schizophrenia-1) regulates differentiation of oligodendrocytes. PLoS One. 2014 Feb 7;9(2):e88506.
  • Gunjima K, Tomiyama R, Takakura K, Yamada T, Hashida K, Nakamura Y, Konishi T, Matsugo S, Hori O. 3,4-dihydroxybenzalacetone protects against Parkinson's disease-related neurotoxin 6-OHDA through Akt/Nrf2/glutathione pathway. J Cell Biochem. 2014 Jan;115(1):151-60. doi: 10.1002/jcb.24643.

2013

  • Koyama Y, Hattori T, Shimizu S, Taniguchi M, Yamada K, Takamura H, Kumamoto N, Matsuzaki S, Ito A, Katayama T, Tohyama M. DBZ (DISC1-binding zinc finger protein)-deficient mice display abnormalities in basket cells in the somatosensory cortices. J Chem Neuroanat. 2013 Nov;53:1-10
  • Magome T, Hattori T, Taniguchi M, Ishikawa T, Miyata S, Yamada K, Takamura H, Matsuzaki S, Ito A, Tohyama M, Katayama T. Neurochem Int. 2013 Sep 24;63(6):561-569.
  • Kondo T, Asai M, Tsukita K, Kutoku Y, Ohsawa Y, Sunada Y, Imamura K, Egawa N, Yahata N, Okita K, Takahashi K, Asaka I, Aoi T, Watanabe A, Watanabe K, Kadoya C, Nakano R, Watanabe D, Maruyama K, Hori O, Hibino S, Choshi T, Nakahata T, Hioki H, Kaneko T, Naitoh M, Yoshikawa K, Yamawaki S, Suzuki S, Hata R, Ueno S, Seki T, Kobayashi K, Toda T, Murakami K, Irie K, Klein WL, Mori H, Asada T, Takahashi R, Iwata N, Yamanaka S, Inoue H. Modeling Alzheimer's disease with iPSCs reveals stress phenotypes associated with intracellular Aβ and differential drug responsiveness. Cell Stem Cell. 2013 Apr 4;12(4):487-96. doi: 10.1016/j.stem.2013.01.009. Epub 2013 Feb 21.
  • Liu HX, Lopatina O, Higashida C, Fujimoto H, Akther S, Inzhutova A, Liang M, Zhong J, Tsuji T, Yoshihara T, Sumi K, Ishiyama M, Ma WJ, Ozaki M, Yagitani S, Yokoyama S, Mukaida N, Sakurai T, Hori O, Yoshioka K, Hirao A, Kato Y, Ishihara K, Kato I, Okamoto H, Cherepanov SM, Salmina AB, Hirai H, Asano M, Brown DA, Nagano I, Higashida H. Displays of paternal mouse pup retrieval following communicative interaction with maternal mates. Nat Commun. 2013;4:1346. doi: 10.1038/ncomms2336
  • Higashida C, Islam MS, Kamimura S, Inoue T, Jin D, Zhang J, Hashii M, Liang M, Zhong J, Hori O, Fukunaga K, Okamoto H, Graeff R, Lee HC, Higashida H*. Dopamine-induced regulation and deregulation of the catabolism of cyclic ADP-ribose, an intrinsic mTOR signal inhibitor, during development in the rodent striatum. Messenger. 2013, 2, 33-43

2012

  • Hashida K, Kitao Y, Sudo H, Awa Y, Maeda S, Mori K, Takahashi R, Iinuma M, Hori O. ATF6alpha promotes astroglial activation and neuronal survival in a chronic mouse model of Parkinson’s disease. PLoS One. 2012;7(10):e47950. doi: 10.1371/journal.pone.0047950. Epub 2012 Oct 24.
  • Nürnberger S, Miller I, Duvigneau JC, Kavanagh ET, Gupta S, Hartl RT, Hori O, Gesslbauer B, Samali A, Kungl A, Redl H, Kozlov AV. Impairment of endoplasmic reticulum in liver as an early consequence of the systemic inflammatory response in rats. Am J Physiol Gastrointest Liver Physiol. 2012 Dec 15;303(12):G1373-83. doi: 10.1152/ajpgi.00056.2012. Epub 2012 Oct 11
  • Kamide T, Kitao Y, Takeichi T, Okada A, Mohri H, Schmidt AM, Kawano T, Munesue S, Yamamoto Y, Yamamoto H, Hamada J, Hori O. RAGE mediates vascular injury and inflammation after global cerebral ischemia. Neurochem Int. 2012 Feb;60(3):220-8. Epub 2011 Dec 19
  • Yamada T, Hashida K, Takarada-Iemata M, Matsugo S, Hori O. α-Lipoic acid (LA) enantiomers protect SH-SY5Y cells against glutathione depletion. Neurochem Int. 2011 Dec;59(7):1003-9. Epub 2011 Oct 1
  • Kinoshita M, Shinohara H, Hori O, Ozaki N, Ueda F, Nakada M, Hamada J, Hayashi Y. Association fibers connecting the Broca center and the lateral superior frontal gyrus: a microsurgical and tractographic anatomy. J Neurosurg. 2012 Feb;116(2):323-30. Epub 2011 Nov 11.

2011

  • Takeichi T, Takarada-Iemata M, Hashida K, Sudo H, Okuda T, Kokame K, Hatano T, Takanashi M, Funabe S, Hattori N, Kitamura O, Kitao Y, Hori O. The effect of Ndrg2 expression on astroglial activation Neurochem Int. 2011, Dec;59(7):1003-9. Epub 2011 Oct 1.
  • Miyata S, Koyama Y, Takemoto K, Yoshikawa K, Ishikawa T, Taniguchi M, Inoue K, Aoki M, Hori O, Katayama T, Tohyama M. Plasma corticosterone activates SGK1 and induces morphological changes in oligodendrocytes in corpus callosum. PLoS One. 2011;6(5):e19859. Epub 2011 May 31.
  • Takarada-Iemata M, Takarada T, Nakamura Y, Nakatani E, Hori O, Yoneda Y. Glutamate preferentially suppresses osteoblastogenesis than adipogenesis through the cystine/glutamate antiporter in mesenchymal stem cells. J Cell Physiol. 2011 Mar;226(3):652-65
  • Takano K, Sugita K, Moriyama M, Hashida K, Hibino S, Choshi T, Murakami R, Yamada M, Suzuki H, Hori O, Nakamura Y. A DIBENZOYLMETHANE DERIVATIVE PROTECTS H2O2-INDUCED CELL DEATH AND INHIBITS LIPOPOLYSACCHARIDE-INDUCED NO PRODUCTION IN CULTURED RAT ASTROCYTES. J Neurosci Res. 2011, Jun;89(6):955-65. doi: 10.1002/jnr.22617. Epub 2011 Mar 21.
  • Wagner AE, Boesch-Saadatmandi C, Breckwoldt D, Schrader C, Schmelzer C, Döring F, Hashida K, Hori O, Matsugo S, Rimbach G. Ascorbic acid partly antagonizes resveratrol mediated heme oxygenase-1 but not paraoxonase-1 induction in cultured hepatocytes - role of the redox-regulated transcription factor Nrf2. BMC Complement Altern Med. 2011 Jan 3;11:1

2010

  • Murakami R, Uchida M, Hori O, Matsuura N, Choshi T, Hibino S, Yamada M. Efficacy of dibenzoylmethane derivatives in protecting against endoplasmic reticulum stress and inhibiting NF-kappaB on dextran sulfate sodium induced colitis in mice. Biol. Pharm. Bull. 2010;33(12):2029-32.
  • Namba T, Hoshino T, Suemasu S, Takarada-Iemata M, Hori O, Nakagata N, Yanaka A, Mizushima T. Suppression of expression of endoplasmic reticulum chaperones by Helicobacter Pylori and its role in exacerbation of NSAID-induced gastric lesions. J Biol Chem. 2010, Nov 26;285(48):37302-13. Epub 2010 Sep 22
  • Miura H, Hashida K, Sudo H, Awa Y, Takarada-Iemata M, Kokame K, Takahashi T, Matsumoto M, Kitao Y, Hori O. Deletion of Herp facilitates degradation of cytosolic proteins. Genes Cells. 2010 Aug;15(8):843-53. Epub 2010 Jul 2
  • Samali A, Fulda S, Gorman AM, Hori O, Srinivasula SM. Cell stress and cell death. Int J Cell Biol. 2010;2010:245803. Epub 2010 Mar 22.
  • Fulda S, Gorman AM, Hori O, Samali A. Cellular stress responses: cell survival and cell death. Int J Cell Biol. 2010;2010:214074. Epub 2010 Feb 21.

2009

  • Hori O. Analysis of astrocyte-derived stress-related genes. Kaibogaku Zasshi. 2009 Dec;84(4):113-4.
  • Takuma K, Fukuzaki, E, Funatsu Y, Nakamichi N, Fang F, Nagai T, Mizoguchi H, Ibi D, Hori O, Ogawa S, Stern DM, Yamada K, Yan SD. Receptor for advanced glycation endproducts (RAGE) promotes intraneuronal transport of amyloid-β contributing to cellular dysfunction. Proc Natl Acad Sci U S A. 2009;106(47):20021-6. Epub 2009 Nov 9.

2008

  • Miura H, Takano K, Kitao Y, Hibino S, Choshi T, Murakami R, Suzuki H, Yamada M, Ogawa S, Hori O. A Carbazole derivative protects cells against endoplasmic reticulum (ER) stress and glutathione depletion. J Pharma Sci. 2008 108(2):164-71.
  • Stanyer L, Jorgensen W, Hori O, Clark JB, Heales SJ. Inactivation of brain mitochondrial Lon protease by peroxynitrite precedes electron transport chain dysfunction. Neurochem Int. 2008 53(3-4):95-101. Epub 2008 Jun 12.

2007

  • Takano K, Tabata Y, Kitao Y, Murakami R, Suzuki H, Yamada M, Iinuma M, Yoneda Y, Ogawa S, Hori O. Methoxyflavones protect cells against endoplasmic reticulum (ER) stress and neurotoxin. Am. J. Physiol Cell Physiol. 2007, 292(1): C353-C361.
  • Tabata Y, Takano K, Ito T, Iinuma M, Yoshimoto T, Miura H, Kitao Y, Ogawa S, Hori O. Vaticanol B, a resveratrol tetramer, regulates endoplasmic reticulum (ER) stress and inflammation. Am J Physiol Cell Physiol. 2007, 293(1):C411-8
  • Takano K, Kitao Y, Tabata Y, Miura H, Sato K, Takuma K, Yamada K, Hibino S, Choshi T, Iinuma M, Suzuki H, Murakami R, Yamada M, Ogawa S, Hori O. A dibenzoylmethane (DBM) derivative protects dopaminergic neurons against both oxidative stress and endoplamic reticulum (ER) stress. Am J Physiol Cell Physiol. 2007 293(6):C1884-94.
  • Miyata T, Takizawa T, Izuhara Y, Kitao Y, Hori O, Ogawa S, Morita Y, Takagi S, and Strihou CY. A novel inhibitor of advanced glycation and endoplasmic reticulum stress reduces infarct volume in rat focal cerebral ischemia. Brain Res. 2007, 1183:124-37
  • Kitao Y, Imai Y, Ozawa K, Kataoka A, Ikeda T, Soda M, Namekawa K, Kiyama H, Stern DM, Hori O, Wakamatsu K, Ito S, Itohara S, Takahashi R, and Ogawa S. Pael receptor induces death of dopaminergic neurons in the substantia nigra via endoplasmic reticulum stress and dopamine toxicity, which is enhanced under condition of parkin inactivation. Human Mol. Genetics. 2007,16(1); 50-60
  • Imuta N, Hori O, Kitao Y, Tabata Y, Yoshimoto T, Matusyama T, Ogawa S. Hypoxia-mediated induction of heme oxygenase type I and carbon monoxide release from astrocytes protects nearby cerebral neurons from hypoxia-mediated apoptosis. Antioxid Redox Signal. 2007, 9: 543-552.
  • Kitao Y, Matsuyama T, Takano K, Tabata Y, Yoshimoto T, Momoi T, Yamatodani A, Ogawa S, Hori O. Does ORP150/HSP12A protect dopaminergic neurons against MPTP/MPP(+)-induced neurotoxicity? Antioxid Redox Signal. 2007, 9: 589-595.

2006

  • Hori O, Miyazaki M, Tamatani T, Ozawa K, Takano K, Okabe M, Ikawa M, Hartmann M, Mai P, Stern M, Kitao Y, and Ogawa S. Deletion of SERP1/RAMP4, a component of the endoplasmic reticulum (ER) translocation sites, leads to ER stress. Mol. Cell. Biol. 2006, 26 :4257-67.
  • Takano K, Kitao Y, Inagi R, Momoi T, Matsuyama T, Miyata T, Yoneda Y, Iso H, Stern DM, Hori O, Ogawa S. A rat model of human FENIB (familial encephalopathy with neuroserpin inclusion bodies). Biochem Biophys Res Commun. 2006, 346:1040-1047